MDBK

Porcine kidney

Epithelial

Both / culture collection

No / 1 / no

Veterinary

only?

Veterinary vaccines

IAV

MDCK

Dog kidney

Epithelial

Both / culture collection

No / 1 / no

Yes

Polarized, growth in CDM

IAV

MRC-5

Human lung

Fibroblast

Adherent / culture

collection

No / 1 / no

Yes

Needs serum, diploid

Polio, measles

PER.C6

Human retinoblast

Suspension / Johnson &

Johnson

Yes / 1 / no

No

Can grow to very high

concentrations (2E08

cells/mL?)

IAV, adenovirus,

PK15

Porcine kidney

Epithelial

Both / culture collection

& ProBioGen

No / 2 / no

Veterinary

only

Growth in CDM

IAV

SF9

Insect

Epithelial

Both / culture collection

No / 1 / no

Yes

Grows at 28°C

Baculovirus

Vero

African green

monkey kidney

Epithelial

Both / culture collection

& NRC

No / 1 / no

Yes

Used for many assays,

available suspension cells

still show very low doubling

times

YFV, SARS, polio,

rabies, HSV1

Please note that there are several subpopulations of cell lines with a different history available, often all running under the same name. Some of these subpopulations may

differ in possible adaptations to growth in suspension, display lower or higher cell-specific virus yields, etc. The list of selected viruses is certainly not complete.

Upstream processing for viral vaccines

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